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          • Proteins & Peptides ›
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          Complement C5 Proteins

          Complement C5 Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed?... Complement C5 Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us... Complement C5 Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... Complement C5 Human recombinant proteins are validated for use in the following applications: Blocking Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

          Protein Information

          C5 (Complement C5) is a Protein Coding gene. Diseases associated with C5 include Complement Component 5 Deficiency and Eculizumab, Poor Response To. Among its related pathways are GPCR downstream signalling and Acquired partial lipodystrophy / Barraquer-Simons syndrome. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and endopeptidase inhibitor activity. An important paralog of this gene is C3. This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants.

          Synonyms

          anaphylatoxin; anaphylatoxin C5; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; C5; C5a; C5a anaphylatoxin; C5b; C5D; Complement C5; Complement C5 alpha chain; Complement C5 alpha' chain; Complement C5 beta chain; complement component 5; CPAMD4; ECLZB; Hc; He; Hemolytic complement; prepro-C5; RGD1561905

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          4 results
          Invitrogen
          Human Complement C5 (aa 1302-1432) Control Fragment Recombinant Protein
          Invitrogen
          Human Complement C5 (aa 1302-1432) Control Fragment Recombinant Protein
          Host
          Species
          Human
          Expression System
          E. coli
          Product Grade
          Research Use Only
          Application
          Ctrl BLOCK
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # RP-95393

          100 µL

          Gibco
          Human C5a Recombinant Protein, PeproTech®
          Gibco
          Human C5a Recombinant Protein, PeproTech®
          Host
          Species
          Expression System
          E. coli
          Product Grade
          Application
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # 300-70-20UG
          Gibco
          Mouse C5a Recombinant Protein, PeproTech®
          Gibco
          Mouse C5a Recombinant Protein, PeproTech®
          Host
          Species
          Mouse
          Expression System
          E. coli
          Product Grade
          Research Use Only
          Application
          Functional
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # 315-40-20UG
          Gibco
          Human C5a, Animal-Free Recombinant Protein, PeproTech®
          Gibco
          Human C5a, Animal-Free Recombinant Protein, PeproTech®
          Host
          Species
          Human
          Expression System
          E. coli
          Product Grade
          Animal-Free
          Application
          Functional
          Price
          Special offer
          Online exclusive
          Online offer:
          Cat # AF-300-70-20UG

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